Sleep, Adults: add 3.5ml to water. Take once a day, at or before bedtime. Take with food to avoid digestive upset. Jet lag: Take once a day at bedtime, while travelling, and at destination until adapted to the new time zone/or daily pattern,Medicinal Per Dosage: Reishi (Ganoderma lucidum – Fruiting body) 500 mg, Chamomile (Matricaria chamomilla – Flower) 150 mg, Melatonin (N-Acetyl-5 -methoxytryptamine) 1 mg Non-Medicinal Ethyl alcohol, Purified water